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195 Clinical drugs, such as sorafenib, 196 sulfasalazine, 197 artemisinin, 198 and ibuprofen, 199 may induce ferroptosis in cancer cells, and ferroptosis inducers combined with temozolomide, cisplatin, haloperidol, and doxorubicin can enhance the chemotherapy effect of these drugs in the treatment of tumors

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and Stanford University have filed a patent application related to this work, PCT/US2023/027896

This smaller opening of the intracellular pocket for G protein is not suitable to engage with the G s protein due to potential steric hindrance (Supplementary Fig

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