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[DOI] [PubMed] [Google Scholar] 23.Kreider RB, Melton C, Rasmussen CJ, Greenwood M, Lancaster S, Cantler EC, et al

Autophagy can regulate the proliferation and size of pancreatic -cells, reduce insulin resistance, prevent diabetic nephropathy, and limit progression of DM through promoting -cell function and eliminating misfolded proteins and dysfunctional mitochondria

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The complexes of such cells and immunoglobulins were cleared by macrophages in vitro and induced a pro-inflammatory cytokine cascade, suggesting that anti-CRP and CRP, along with these cells, create a ternary pyrogen endowed with strong proinflammatory capabilities that aid in the maintenance of chronic inflammation [171]