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After injury, the kidney reprograms to shift its energy reliance, which increases its oxygen consumption, becoming more vulnerable to hypoxia and oxidative injury 16,17

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To construct the shRNA knockdown vector pLKO.1-GST DAF , we inserted the GST-EGFP-GPI DAF coding region into the pLKO.1 puro plasmid in place of the puromycin resistance gene

Biochemical indicators of vitamin B12 and folate insufficiency and cognitive decline