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Whether youre a marathon runner or a weekend warrior, theres a lot of buzz around using supplements to enhance your workouts

It uses a methyl group donated by S-adenosylmethionine (SAM) to methylate nicotinamide a vitamin B3 form that would otherwise be recycled back into NAD+

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It plays a crucial role in detoxification, helping the liver remove toxins and heavy metals from the body

(Created with biorender.com) Thus, it is questionable whether this mechanism can be applied to other cell types, particularly hepatocytes with their complex, multi-layered antioxidant systems