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Baicalin and formononetin significantly upregulate the expression of filaggrin and loricrin, reduce TEWL, suppress mast cell infiltration, and ameliorate both epidermal disruption and modified Eczema Area and Severity Index (EASI) scores in AD mouse models (Wang L

Intraperitoneal T4 administration following lipopolysaccharide (LPS) injection reduced pro-inflammatory cytokines in mouse plasma [241]

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Finally, VB124 selectively targets MCT1 in hepatocellular carcinoma, disrupting lactate shuttling between tumor and stromal cells to reduce growth without overt toxicity 162,163