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Aliment Pharmacol Ther 11:787791

Birukov KG.2006Oxidized lipids: the two faces of vascular inflammationCurr Atheroscler Rep83223 EOF231 EOF1534-6242 9
Specifically, we seek to evaluate the effects of PCOS on DNA methyltransferase (DNMT) gene expression (DNMT1, DNMT3a, DNMT3b), oxidative stress markers (glutathione peroxidase, catalase, superoxide dismutase, glutathione reductase, glutathione, and malondialdehyde), and trace element levels (zinc, copper, magnesium, and Fe) in ovarian tissue, serum, and liver

doi: 10.2337/diabetes.47.10.1578

Under oxidative stress, DNA methyltransferases DNMT1 and DNMT3B, along with sirtuin SIRT1, relocate to CpG islands (CGIs) and form complexes with PRC2 subunits like EZH2 and EED, leading to localized DNA methylation (172)
