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The ensuing cytochrome C efflux activates caspase-9 and caspase-3, while ROS-induced DNA damage stabilizes p53, shifts the Bax/Bcl-2 balance toward apoptosis [65], and upregulates Fas/FasL signaling [66]

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Inflammation is a natural response during wound healing, but excessive or prolonged inflammation can delay the healing process

D.1994Regulation of aflatoxin B1-metabolizing aldehyde reductase and glutathione S-transferase by chemoprotectors.300117124 57
Testa B, Pedretti A, Vistoli G
