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NAC, a powerful scavenger of OH,40 could effectively prevent cytokine storm and ROS-induced pulmonary edema and respiratory failure

Biochem Pharmacol (2017) 143:3952.10.1016/j.bcp.2017.07.006 Summary Keywords tumors, mitochondria, metabolism, proteoliposome, plasma membrane, drug design Citation Scalise M, Pochini L, Galluccio M, Console L and Indiveri C (2017) Glutamine Transport and Mitochondrial Metabolism in Cancer Cell Growth

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Yamada Y, Akita H, Kamiya H, Kogure K, Yamamoto T, Shinohara Y, Yamashita K, Kobayashi H, Kikuchi H, Harashima H (2008) MITO-Porter: a liposome-based carrier system for delivery of macromolecules into mitochondria via membrane fusion

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Abnormally regulated homeostasis of enzymes results in mitochondrial dysfunction, eNOS uncoupling, formation of secondary ROS, and disturbed metabolism of redox and non-redox active metals