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Facchinello N, Astone M, Audano M, Oberkersch RE, Spizzotin M, Calura E, et al
Mechanisms: By lowering chronic low-grade inflammation without suppressing normal immune defense, KPV creates a permissive biological environment for tissue renewal
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This activity was achieved by modulating genes expression (APAF1, Mcl-2, VEGF, cyclin-D1, ZEB1 and caspase-3) associated with cancer development [167]
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