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In particular, it demonstrates that polymer nanoparticles with tailored physicochemical properties, such as size, shape, and surface charge, can efficiently cross the BBB

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Am J Respir Cell Mol Biol 41:509515 Corti A, Franzini M, Paolicchi A, Pompella A (2010) Gamma-glutamyl transferase of cancer cells at the crossroads of tumor progression, drug resistance and drug targeting

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they are a proven therapy and a research compound whose clinical development was abandoned in 2007

10.1038/s41416-019-0482-x Br
