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doi: 10.1186/s12937-022-00812-x 69
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51 For example, integrins, which are transmembrane receptors, mediate the interaction between the extracellular matrix and the cytoskeleton, influencing cell behavior and tissue remodeling

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CRP caused mechanical and thermal hyperalgesia in rats after intraplantar injection, and overexpression in the dorsal root ganglion (DRG) correlated with increased pain behaviors, indicating a potential role for CRP at the DRG level in modulating nociceptive signaling (Liu et al., 2023)

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