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But at higher concentrations like 20mg/mL, 1 unit of dead space equals 200mcg, and 5 draws waste 1,000mcg (1mg), which is 5% of a 20mg vial

Each depends, in part, on adequate levels of vitamin B12

Using simple sterile water is an option for single-use applications, but for any protocol requiring multiple draws from the same vial, bacteriostatic water is the only acceptable choice