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When introducing any IV fluids to the system, careful calculations must be made to ensure that the administered solution is of a comparatively similar electrolyte concentration to the body to maintain this equilibrium

Fumarate itself is a Michael acceptor, and the covalent attachment to protein cysteines corresponds to the post-translational modification known as succination [142] and fumarate has been recently demonstrated to yield a glutathione thioether in in vitro treated cells [142]

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doi: 10.1016/s0065-2571(00)00013-3

Glutathione is a vital component in removing harmful toxins, eliminating cellular inflammation, and neutralizing free radical damage

Code availability Code, data files and workflows generated for these analyses are available in a GitHub repository at Source data for scMEP CyTOF analysis are provided in within the source data file