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In recent years, studies have shown that activation of FAO is correlated with biological behaviors of tumor cells, such as survival, proliferation, invasion, metastasis, and drug resistance [21]

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Notably, the addition of guanine nucleotides converted high to low-affinity state receptors (by promoting heterotrimeric G-protein dissociation)

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have designed ROS-scavenging and iron-chelating polymers with thioester and thioketal bonds to deliver Liproxstatin-1 (Lip-1), another radical-trapping antioxidant that inhibits ferroptosis, forming a triple therapeutic strategy for acute glaucoma