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In conclusion, we suggest that APR-246 exerts its cytotoxic effect through various cell death pathways

About this article Cite this article Aguirre, G.A., De Ita, J.R., de la Garza, R.G
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The FUS RRM mutant construct (pUAST -FUS-RRMmut ), in which leucine residues at positions 305, 341, 359, and 368 in the FUS protein were substituted to phenylalanine, was generated by PCR and the In-Fusion Cloning system (Takara Bio)
Aging (Albany NY) 2016, 8 (2), 304-13

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