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Selenium supplementation reduces fasting plasma glucose (FPG), cholesterol, insulin, and TC levels (36)

doi: 10.1111/j.1398-9995.2009.02220.x

People with liver or kidney disease , or a history of organ dysfunction

J Bioenerg Biomembr 32:401411 Sawada H, Takami K, Asahi S (2005) A toxicogenomic approach to drug-induced phospholipidosis: analysis of its induction mechanism and establishment of a novel in vitro screening system

doi: 10.1002/dmrr.v34.3 267 WuDWuCZhongY

The specific mechanisms by which elevated homocysteine contributes to cardiovascular pathologies and whether interventions to lower homocysteine levels are beneficial remain areas of debate and investigation
