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Retatrutide dose levels tested in clinical trials The Phase 2 trial published in the New England Journal of Medicine tested four dose tiers against placebo over 48 weeks

Tkalcevic, V., et al

10.1016/s0196-9781(02)00083-9 41 FuM.YuX.LuJ.ZuoY

S.DehsarviA.StewardA.et al (2025)

doi: 10.1097/00007890-199310000-00007

Lillys triple agonist retatrutide has reported weight loss of up to 30% in phase 3, with the pivotal TRIUMPH-1 trial reporting 28.3% at 80 weeks in a population of more than 2,300 adults with obesity
