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Description
It is becoming increasingly clear that there is a massive energetic deficiency in AD brains that is paired with mitochondrial dysfunction, it is possible that such pathologies and loss of function precede the actual neuronal death itself
Misganaw A
Mol Cell Proteomics (2012) 11(2):M111 013904
Figure 2 shows the VCE images of the two groups
Signs and symptoms [edit] Symptoms typically start between the ages of 5 and 15, but in late-onset FRDA, they may occur after the age of 25 years
(b) glucose-6-phosphate to fructose-1,6-bisphosphate
