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This damage worsens neuronal dysfunction and accelerates disease progression

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Systematic reviews note that existing human data comes largely from small observational studies or case reports, many with methodological limitations

For products stored at -20C, this process takes more than 1 hour, depending on the size of the package

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Both the PI3K/Akt and Ras/MAPK signaling will phosphorylate the proapoptotic protein BAD, causing inactivation due to cytoplasmic sequestration, which leads to enhanced platinum resistance by blocking apoptosis [114]