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b , Relative expression of interferon-stimulated genes (ISGs) in the BALF of patients with severe COVID-19 ( n = 13 ) and patients with influenza ( n = 7 )

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Upon activation by microbial PAMPs and other stress-related molecules, NLRP3 leads to the activation of caspase-1 followed by cleavage of pro-IL-1 into its active IL- form, which promotes further inflammatory signaling

This type of acne treatment is generally well-tolerated and can be effective in reducing both active acne and acne scars

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