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This helped to show that NNMT is a key target in metabolic research. Neelakantan and colleagues then expanded research involving small-molecule NNMT inhibitors

Such biomarkers could help identify patients most likely to respond to treatment and could facilitate personalized treatment approaches

Mitochondria contain cholesterol side-chain cleavage enzyme, P450scc, ferredoxin, and ferredoxin reductase providing an essential site for steroid hormones biosynthesis

Additionally, there have been studies utilizing materials science to improve the therapeutic effect of FGF-21 for AD