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doi: 10.1124/jpet.117.244368

PASC that persist for more than 4 weeks after the acute infection are termed long COVID [12, 26, 31], with varying incidences between 10 and 70% of infected COVID-19 patients developing long COVID symptoms, depending on the study population examined, e.g., non-hospitalized, hospitalized or vaccinated patients, etc

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TRIM33 is an E3 ubiquitin ligase, which can promote SMAD4 ubiquitination and induce SMAD4 to export from the nucleus, thereby inhibiting transcriptional activity of SMADs