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This finding may suggest an important role of detoxifying transformations in UA metabolism, the consequences of which for the anticancer and/or toxic activities of the compounds are not yet well understood

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The substrates and products of the DHODH reaction have opposite effects on ferroptosis, suggesting that the potential role of DHODH in regulating ferroptosis sensitivity is independent of its function of producing pyrimidine nucleotides

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Monitoring the Effects of Glutathione Supplementation 4