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Key research questions are identified and systematically reviewed such as: (i) what are the key factors responsible for the dysregulation of mtROS production

Funding This study was supported by a research grant (3251) from Shahrekord University of Medical Sciences, Shahrekord, Iran

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In this study we investigated the specific sites of PARP1-mediated PXR ribosylation, particularly regarding their functional relevance to CYP3A4-driven NAPQI biosynthesis in AILI

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Matrix metalloproteinases (MMPs) are up-regulated by pro-inflammatory cytokines, as well as by acute phase proteins like serum amyloid A (SAA), with counter-regulatory inhibition by IL-4 and IL-13, and released into the circulation from damaged vascular endothelium