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Remarkably, physical exercise, particularly swimming, can lead to increased glucose uptake also by upregulating GLUT4 expression, thus contributing to improve glycolysis, as revealed by the enhanced lactate production (Scaricamazza et al., 2020)

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10.1126/science.1059497 Science 35 FarooqZ.BandayS.PanditaT

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Cellular assays confirmed PVs ability to suppress ROS in macrophages, while network pharmacology and mRNA/protein validation identified key molecular targets (e.g., BCL2L1, ESR1, JAK2/STAT3), revealing a broader biological impact