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Epilepsia , 56 (10), 15151523

Methods 20 , 11791182 (2023)

Similar content being viewed by others Background The ketogenic diet (KD), a high-fat, low-carb dietary therapy, is being increasingly accepted worldwide as a practical, effective and safe management alternative in children and adults with refractory epilepsy (RE), which is defined by the International League Against Epilepsy (ILAE) as failure of adequate trials of two tolerated, appropriately chosen and used antiepileptic drug (AEDs) schedules to achieve sustained seizure freedom [1, 2]

Statistical Methods Results are expressed as mean SEM