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doi: 10.1186/s12906-019-2635-0, 18
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Nature 390 , 91 (1997)
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As ROS accumulate excessively, the mitochondrial outer membrane protein Tom20 and the Bax pathway are altered, leading to the release of cytochrome c and other pro-apoptotic/pro-pyroptotic molecules from mitochondria, thereby activating the downstream caspase cascade
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