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Male participant (age 51) RESULTS: *The oxidative stress market F2-Isoprostane decreased by 55% in the first 14 days, maintaining a 52% decrease after 28 days

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Belichenko PV, Oldfors A, Hagberg B, Dahlstrm A

doi: 10.1021/JF048398W 277 VissersYMBlancFSkovPSJohnsonPERigbyNMPrzybylski-NicaiseLet al

Erastin triggers ferroptosis in colorectal cancer cells by activating the PERK-NRF2-HO-1 signaling pathway, thereby exerting potent anti-tumor effects ( 3 Ferroptosis and NAFLD 3.1 Ferroptosis and inflammation Globally, the prevalence of NAFLD continues to rise, encompassing a spectrum of conditions from simple steatosis to NASH, fibrosis, and cirrhosis (45)

A more recent study demonstrated that when mice carrying a mutation associated with myelin defects were crossed with transgenic mice, the offspring exhibited early-onset deposition of A in the brain, in comparison to age-matched controls [56]