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10.1016/j.actbio.2018.12.046 87 Garca-FernndezA.SanchoM.BisbalV.AmorsP.MarcosM

At the crossroads of inflammation and cancer

Oxidative stress is one of the most important causes of T cell-mediated autoimmune disorders of the central nervous system and is important for the progression of experimental allergic encephalomyelitis (EAE) (Majdalawieh and Fayyad, 2015

Specifically, 10 L of the ITC was mixed with 25 mg of GSH, Cys-Gly, or Cys in 10 mL of water:ethanol (1:1, pH = 7) at room temperature for 48 h

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While most CIPN occurs in a dose dependent fashion, other drug-specific features may be present such as the acute neurotoxicity of paclitaxel and oxaliplatin, or the worsening of neuropathy after discontinuation of cisplatin (coasting)