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Modeling PD pathogenesis in mice: advantages of a chronic MPTP protocol

Ascorbate stimulates dietary iron absorption, contributes to plasma transferrin-bound iron uptake following binding of the transferrin-iron complexes to the plasma membrane transferrin receptor, stimulates the synthesis of the iron storage protein ferritin, inhibits lysosomal ferritin degradation, and inhibits cellular iron efflux
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This may be due to the measurement of the combined peak of glutamate and glutamine or the need for more time or a steady-state concentration of NAC to increase the activity of metabotropic glutamate receptors and to downregulate synaptic glutamate release

83 , e00034-19 (2019)

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