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12 A systematic review (N = 18 trials) evaluated the effects of long-term inhaled antibiotic therapy on lung function and exacerbation frequency in CF individuals

122,123 By observing the impact on the disease phenotype, researchers can establish the causal relationship between the target gene and the disease

Diabetes Care 2010 (in press)

doi: 10.1016/j.jaci.2009.02.028
10.2337/dc07-2173 44 Fernndez-RealJ

doi: 10.1016/S0022-474X(99)00056-9
