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The observation that BDNF over-expression in mice increased the number of dendritic spines and dendritic connectivity, and also increased cognitive performance, as observed using live imaging [56,57], could suggest that BDNF has some degree of potential for refining circuits through synaptic pruning and stability

The procedure generally lasts 1530 minutes, depending on the number of trigger points treated

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Importantly, despite the existing evidence for low-level protein translation in erythrocytes [41], protein synthesis in mature erythrocytes is negligible or virtually absent, and erythrocytes cannot regulate cell death by production of cell death-associated proteins

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These findings suggest that FR may participate in early dopaminergic lineage specification or maturation, although its precise functional role in vivo remains to be clarified