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The relatively constant increase in GS activity under the same conditions (Table 2) was most likely due a combination of an increase in glnA1 transcription and very strict control of GS activity by the adenylyltransferase, GlnE, in order to balance ammonium assimilation
doi: 10.1172/JCI81919

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Also in this setting, the potency of FOXO4-DRI was more pronounced when applied in consecutive rounds Not only did FOXO4-DRI selectively target the senescent cells, but it was also effective agains the induced chemo-toxicity observed in the form of liver toxicity and body weight loss
53, 12831304.10.1093/jexbot/53.370.939 48 NoctorG.StrohmM.JouaninL.KunertK