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DOI: 10.1159/000126922 35

The vacuole is also involved in the cysteine sulfur conversion into H 2 S/sulfane sulfur, as mutants affected in vacuole acidification, vacuolar transport or vesicle fusion show dramatically lower H 2 S/sulfane sulfur production from cysteine (Winter et al., 2014), this being potentially linked to impaired cysteine partitioning into the vacuole

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The melatonin synthesized by both pineal gland and extrapineal glands coordinate with each other to regulate immune molecules, including pathogen-associated molecular patterns (PAMPs), danger-associated molecular patterns (DAMPs), toxic A, heat-shock proteins, and tissue debris [67]

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