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Parasitized erythrocytes are sequestrated in the splanchnic vasculature and cause local ischemia that induces intestinal dysbiosis, and increased intestinal permeability and translocation of bacterial products [68]

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Cell 144(5):646674

Acknowledgements We are grateful to the National Natural Science Foundation of China (21276112 and 21506073), a Grant from Science and Technology Commission of Shanghai Municipality (15JC1400403), the Natural Science Foundation of Jiangsu Province (BK20150003), the Fundamental Research Funds for the Central Universities (JUSRP51409B), the Program of Introducing Talents of Discipline to Universities (111-2-06), and a project funded by the Priority Academic Program Development of Jiangsu Higher Education Institutions for the financial support of this research

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Pain Modulation DSIP has demonstrated analgesic properties in several animal studies