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Indeed, even though 99% of NF1 patients meet the diagnostic criteria (Box 1) 1 by the age of 20 years, 2 the manifestations are unpredictable even within the same family harbouring an identical mutation

Plasma metabolomics analysis showed that LC differed from the R and HC groups

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The emotional challenges faced by parents before treatment are also highlighted, with one describing their childs frustrations and meltdowns as heart-breaking

[DOI] [PubMed] [Google Scholar] 41.Yan J, Yu J, Wang C, Gu Z