oral mucosal melanotic lesions COM Jan. 2008 Diagnosis Oral Malignant Melanoma - Oral

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doi: 10.1016/j.cell.2009.01.025

These investigations demonstrate the feasibility of in vivo CRISPR interventions to reverse fundamental ALS processes, while also emphasizing the problems of delivery, immunogenicity, and product purity (editing byproducts) that persist for clinical application (227)

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Another deletion allele, gk405 , shortens lifespan to a similar extent (Lee et al., 2019)