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While these three components are all directly related to ghrelin, one cannot deny the complex interrelationships between ghrelin and the multitude of other systems beyond simply the typical endocrine and feeding effects of this peptide

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[DOI] [PubMed] [Google Scholar] Rushmore TH, Morton MR, et al
In addition, another study recruited 33 pregnant women between 16 and 22 weeks of gestation, among them, 19 patients were smokers and 14 were nonsmokers

Its human safety profile is not established there is no completed human trial
