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Melatonin improves stroke through MDM2-mediated ubiquitination of ACSL4

Nanoenzymes that are said to be functionalized, could be used for controlling and repairing/regenerative, at a molecular level, prion, amyloid protein misfolding with limited clearance, cytokines release inhibitors or enhancers, enzymes activators or depressors, antibodies, signaling molecules, RNA, enhancer or repressor factors, stem cells, as a challenge

Therefore, adding glycine deficiency to reduced levels of cysteine and glutathione would likely have an additive effect on 5-oxoproline generation and may develop in malnourished, chronically ill patients

Dedication This work is dedicated to Dr

doi: 10.3389/fphar.2025.1586231 Received 21 March 2025 Accepted 30 April 2025 Published 09 June 2025 Volume 16 - 2025 Edited by Irwin Rose Alencar de Menezes, Regional University of Cariri, Brazil Reviewed by Alaaeldin Ahmed Hamza, National Organization for Drug Control and Research (NODCAR), Egypt Mohannad A

Therefore, to overcome this drawback, a formulation form that can be injected intramuscularly, subcutaneously or intravenously should be developed at a later stage