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doi: 10.1086/507566

Tanaka K, Sasayama T, Irino Y, Takata K, Nagashima H, Satoh N, et al

Metabolic reprogramming as a key regulator in the pathogenesis of rheumatoid arthritis

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The target Cys must be located: (i) in an immediate vicinity to the NO source, (ii) within the protein I/LXCX 2 D/E motif specifically recognized by NOS, (iii) in a highly hydrophobic region created by the tertiary protein structure or membranes, (iv) in a proper microenvironment allowing thiolate anion formation [105]

How to include it: Roast chicken with skin on for Sunday meals Add to bone broth or stew for added flavor and nutrient density Use in soups or curries where texture is appreciated 3