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Water was available ad libitum

Conclusion Evidence has shown that NNMT plays important roles in obesity and T2D and that NNMT inhibition significantly increases energy expenditure, reduces body weight and white adipose mass, improves insulin sensitivity, and normalizes glucose tolerance and fasting blood glucose levels

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10.1016/j.cjca.2012.03.013 17 ButkowskiE

[DOI] [PMC free article] [PubMed] [Google Scholar] 11.Martinussen C, Bojsen-Moller KN, Svane MS, Dejgaard TF, Madsbad S

GLP-1 agonists work primarily through appetite suppression and slower gastric emptying