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NUPR1 is a critical repressor of ferroptosis

[DOI] [PubMed] [Google Scholar] 43.Glycine and N-acetylcysteine (GlyNAC) supplementation in older adults improves glutathione deficiency, oxidative stress, mitochondrial dysfunction, inflammation, insulin resistance, endothelial dysfunction, genotoxicity, muscle strength, and cognition: results of a pilot clinical trial

This approach demonstrates strong potential for neuroprotection in PD by alleviating oxidative damage and preserving dopaminergic neurons (Soni and Kumar, 2022)

One study examined the impact of AST on neurotoxicity in a PD mouse model of young and aged mice

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[2] Reduces Inflammation: Oxidative stress triggers inflammation