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Although the precise prevalence of painful peripheral neuropathy in cirrhosis remains elusive, research has revealed that 15% of cirrhotic patients manifest neuropathic symptoms such as numbness and paraesthesia ( 10.3 Treatment and adjunctive management General principles include addressing comorbid symptoms (such as sleep, mood, memory, fatigue, and psychiatric disorders), emphasizing self-management tools, and employing multimodal therapies that combine several non-pharmacologic strategies

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Shahriarinour M, Divsar F, Eskandari Z

doi: 10.1096/fasebj.7.8.8500689

L.IkedaS.WaynerM