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However, many people may be deficient in this essential vitamin due to factors such as dietary restrictions, certain medical conditions, or lifestyle choices

Brain 121, 889905 [DOI] [PubMed] [Google Scholar] Barttfeld P., Wicker B., Cukier S., Navarta S., Lew S

Although the focus of this review is to examine the impact of selenium and myo-inositol in the context of thyroid disease, there is limited evidence to support the use of myo-inositol alone in the treatment of thyroid disease

Despite initial enthusiasm for cuproptosis as a novel pathogenetic mechanism [27,51,54] , the molecular and metabolic complexities underlying copper-dependent hepatocellular injury in Wilson disease remain unresolved, especially since the role of ROS and reactive copper intermediates was not originally included in the cuproptosis framework [51,54]

Symptoms of B12 deficiency, which can develop over years, may include fatigue, pale skin, numb or tingly hands or feet, and confusion

Moreover, vitamin C plays a crucial role in regulating iron metabolism by promoting ferroportinmediated iron export and inhibiting hepcidin expression