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dsip benefits for insomnia & Epitalon: A Functional Medicine Approach to Restorative Sleep Dr. Richman on DSIP: The
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doi: 10.3390/metabo12060508
[232] [198] In addition to presynaptic actions that regulate DAT, TAAR1 activation exerts a somatodendritic inhibitory influence on midbrain dopamine neurons by reducing their firing rate via G protein-coupled inwardly-rectifying potassium channels, an effect that is expected to reduce action potential-dependent (vesicular) dopamine release into the synaptic cleft
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