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The core objective of these strategies is to address the complex, multi-system pathological mechanisms of PD, aiming to achieve superior overall efficacy compared to single-target therapies through synergistic interventions at different pathological nodes

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and (ii) reduced lung metastasis following tail vein injection of TNBC cells in combination with chemotherapy (carboplatin) but not immunotherapy (anti-CTLA4 plus anti-PD1)

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