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Some examples include the phosphatidylinositol 3kinase/protein kinase B (PI3K/AKT) and the mitogenactivated protein kinase (MAPK) pathways (55)

Importantly, ADAM17 is a protease suggested to be involved in 1 -AR-mediated transactivation of the epidermal growth factor receptor (EGFR) (Noma et al., 2007)

PLoS One 12 (7), e0181978

Combined use of immune checkpoint inhibitors and phytochemicals as a novel therapeutic strategy against cancer

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Osteopontin and CD44, markers of the HFSC niche, were also increased