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p300/CBP keeps chromatin silent
Alcoholics show increased susceptibility to paracetamol over-dosage because excess alcohol consumption results in the depletion of glutathione (Lauterburg and Velez, 1988) and induction of the P450 isoform CYP2E1 (Raucy et al ., 1989)
World J Gastroenterol (2012) 18:302
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PMID: 39290981
This article reviews the research progress on the pharmacological mechanism, clinical application and safety of YNBY in the past two decades
