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This kinase cascade is part of the broader MAP kinase signaling network that regulates cell proliferation, differentiation, and stress response pathways

However, more severe oxidative stress can cause cell death, and even moderate oxidation can trigger apoptosis, while more intense stresses may cause necrosis
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Adv Healthc Mater 10:150

Injectable GHK-Cu went through the Category 2 process entirely separately and is on the later review track
