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Blood-borne phagocytes internalize urate microaggregates and prevent intravascular NETosis by urate crystals

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The supernatant was obtained by centrifugation (10000 g for 5 min at 4C) and filtered using 0.45 m filter

Ferroptosis contributes to OA through several mechanisms: 1) Iron overload and lipid peroxidation: elevated iron levels in OA tissues lead to increased lipid peroxidation, which damages cell membranes and induces cell death

Mechanism-Based Combinatorial Strategy for Overcoming FLT3-Inhibitor Resistance in Dual FLT3 ITD and TKD Point Mutations

doi:10.3390/cells9051134 67